Version 29 makes official unveil of the "methylC" track, though it has been available on our browser for a while.
The methylC track is able to display single-base DNA methylation data by discerning cytosine context (CG/CHG/CHH), strand-specificity, and incorporating confidence level data.
Thus it is excellent in visualizing whole-genome bisulfite sequencing (WGBS, or methylC-seq) results. In this case the confidence level data is read depth.
Surely it makes same support on Reduced Representation Bisulfite Sequencing (RRBS) results.
It can even be used for array-based methods such as Infinium 450K. In this case the -log10(P-value) will be used as confidence level.
Refer to http://epigenomegateway.wustl.edu/+/cmtk/ for more details.
A manuscript describing methylC track is under preparation.
The methylC track is able to display single-base DNA methylation data by discerning cytosine context (CG/CHG/CHH), strand-specificity, and incorporating confidence level data.
Thus it is excellent in visualizing whole-genome bisulfite sequencing (WGBS, or methylC-seq) results. In this case the confidence level data is read depth.
Surely it makes same support on Reduced Representation Bisulfite Sequencing (RRBS) results.
It can even be used for array-based methods such as Infinium 450K. In this case the -log10(P-value) will be used as confidence level.
Refer to http://epigenomegateway.wustl.edu/+/cmtk/ for more details.
A manuscript describing methylC track is under preparation.
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