Sunday, November 24, 2013

v29 (4 of 4): the methylC track

Version 29 makes official unveil of the "methylC" track, though it has been available on our browser for a while.

The methylC track is able to display single-base DNA methylation data by discerning cytosine context (CG/CHG/CHH), strand-specificity, and incorporating confidence level data.

Thus it is excellent in visualizing whole-genome bisulfite sequencing (WGBS, or methylC-seq) results. In this case the confidence level data is read depth.

Surely it makes same support on Reduced Representation Bisulfite Sequencing (RRBS) results.

It can even be used for array-based methods such as Infinium 450K. In this case the -log10(P-value) will be used as confidence level.





Refer to http://epigenomegateway.wustl.edu/+/cmtk/ for more details.

A manuscript describing methylC track is under preparation.